大家在查：王肖广内胞南·高登阿瑟·萨维尔 Scamander 瓦瓦乌 •瓦斯 jiance ClaudiaGoldinandLawrenceKatz 亚瑟·萨维尔

奥美沙

奥美沙

奥美沙

奥美沙

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The higher rate of fatal cardiovascular events with olmesartan among patients with preexisting coronary heart disease is of concern .

值得注意的是在有冠心病史的患者中，奥美沙坦引起的致死性心血管事件发生率较高。

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The combination of olmesartan with a diuretic has a stronger effect on BP lowering compared to olmesartan or diuretic alone .

与单用奥美沙坦或利尿剂相比，奥美沙坦与利尿剂联合有更强的降压效应。

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And what are the special benefits of olmesartan-based combination compared with other ARBs-based combinations ?

基于奥美沙坦的联合治疗有何特殊益处？

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Overall, treatment-related adverse events were not significantly increased in patients receiving olmesartan-based therapy.

在接受奥美沙坦为主的治疗组中，与治疗相关的不良反应在总体上没有显著增加。

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What are the determinants making olmesartan the strongest anti-hypertensive ARB?

使奥美沙坦成为最强效抗高血压 ARB 的决定因素是什么？

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A pos-hoc analysis of ROADMAP demonstrated a "substantial BP-independent effect " of olmesartan in preventing microalbuminuria .

ROADMAP 事后分析显示奥美沙坦预防微量白蛋白尿（MAU ）具有 “可观的独立于 BP 之外的作用 ”。

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abstract: Objective : To evaluate the efficacy and safety of olmesartan medoxomil on hypertension in elderly patients.

目的：评价奥美沙坦酯治疗老年高血压的疗效和安全性。

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So what 's the difference between olmesartan-based combination therapy and other ARBs-based combination therapy ?

基于奥美沙坦与基于其他 ARB 制剂的联合治疗相比有何不同？

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According to these findings can we conclude that treatment with olmesartan will bring us more promising benefits in reducing CVD risk ?

根据这些发现，我们是否可以得出结论，即奥美沙坦治疗可以带来显著降低 CVD 风险的获益？

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Conclusion : Olmesartan medoxomil is effective and safe in the treatment of hypertension in elderly patients.

结论：奥美沙坦酯治疗老年高血压效果明显，安全性好。

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AIM : To investigate the protective effect of olmesartan medoxomil on renal injury in mice with chronic heart failure (CHF).

目的：探讨奥美沙坦酯对慢性心力衰竭小鼠肾脏损伤的影响。

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Other lecturers spoke this evening about ARBs and in particular olmesartan.

今晚的其他演讲谈及 ARBs ，尤其是奥美沙坦。

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Are there any particular factors that make olmesartan a stronger ARB?

哪些特殊因素使得奥美沙坦成为降压作用更强的 ARB ？

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Prof. Zhu : Compared to other ARBs, olmesartan has the strongest effects of BP lowering .

朱鼎良教授：与其他 ARB 相比，奥美沙坦有最强的降压作用。

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It is clear that olmesartan has a very good position in the armamentarium to control blood pressure .

显然，在全部药物中，奥美沙坦在控制血压方面有非常重要的地位。

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In addition , data from the ROADMAP study proved that olmesartan can reduce risk of MAU in T2DM patients .

另外，来自 ROADMAP 研究的数据证明，在 T2DM 患者中奥美沙坦可降低 MAU 风险。

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I think this is the effect of olmesartan complete reverse agonism and also underlying mechanism of olmesartan makes it the strongest ARB.

这是奥美沙坦的完全反向激动效应，也是其成为最强效 ARB 的潜在机制。

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Antihypertensive efficacy and safety of domestic olmesartan monotherapy in mild or moderate essential hypertension

国产奥美沙坦单药治疗轻、中度原发性高血压的疗效和安全性

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